Senior Research Engineer (Computing & Intelligence), IHPC

At the Institute of High Performance Computing (IHPC), ASTAR, we drive innovation at the intersection of artificial intelligence and healthcare. Our mission is to build large language models (LLMs) and multimodal foundation models that can transform clinical decision support, biomedical discovery, and public health. We are looking for AI Engineer with strong applied AI skills ready to build large-scale systems. You will contribute to innovations that make real impact in healthcare. Key Responsibilities: Research & Development Develop novel architectures, training strategies, and optimization methods for LLMs and multimodal foundation models. Advance instruction tuning, reinforcement learning (RLHF/GRPO), retrieval-augmented generation (RAG), and knowledge-grounded reasoning in medical AI. Design and implement multimodal learning pipelines that integrate text, imaging, omics, and real-world clinical data. Translation & Collaboration Prototype AI systems for clinical and biomedical applications (e.g., decision support, conversational AI, population health, drug discovery). Benchmark models against state-of-the-art healthcare AI datasets and evaluation frameworks. Collaborate with industry and healthcare partners to enable translation, licensing, and commercialization. Scientific Leadership Publish in top-tier AI/ML venues (e.g., NeurIPS, ICML, ICLR, AAAI, ACL) and high-impact biomedical journals (e.g., Nature Medicine). Contribute to open science initiatives (datasets, model releases, benchmarks). Secure funding through collaborative research proposals with academia, healthcare institutions, and industry. Job Requirements: Bachelor’s or Master’s degree in Computer Science, Artificial Intelligence, or related fields. Proven hands-on experience in implementing and optimizing machine learning models. Proficiency in Python and deep learning frameworks (PyTorch, TensorFlow, JAX). Experience with large-scale training, HPC workflows, or ML engineering pipelines. Experience in large-scale LLM and foundation model training and deployment. Experience with medical or biomedical data (EHR, clinical notes, imaging, genomics). Familiarity with biomedical ontologies and knowledge graphs (UMLS, SNOMED CT, PubMed). Understanding of AI ethics, safety, and regulatory considerations in healthcare. The above eligibility criteria are not exhaustive. ASTAR may include additional selection criteria based on its prevailing recruitment policies. These policies may be amended from time to time without notice. We regret that only shortlisted candidates will be notified.